Furthermore, the expression levels of SNRPB2 protein in ESCC were significantly correlated with vessel carcinoma embolus and lymph node metastasis, (both P < 0.05) but not with patient age, sex, BMI, smoking or drinking history, tumor location, or nerve invasion (all P > 0.05) (Table 2; Supplementary Figure S1e). The gene discussed is SNRPB2; the disease is metastatic malignant neoplasm in the lymph nodes.