SNRPB2 and neoplasm: We found that SNRPB2 mRNA was highly expressed in ESCA samples compared to normal samples, and similar results were observed in paired samples (both P < 0.05, Supplementary Figure S1c; Figure 1b), while no significant correlation between SNRPB2 mRNA expression and tumor stage was observed in this dataset (P > 0.05, Supplementary Figure S1d).