Ultimately, 8 key genes were identified: CD160, HELB, ING4, PIP5K1C, SRPRA (HR < 1); and CDCA7, FAM3A, PPP1R15A (HR > 1), and the hub genes showed apparent differences in expression between alive and dead sepsis patients (Figure 3B). The gene discussed is FAM3A; the disease is Sepsis.