It has been proposed that the ultimate goal for people with haemophilia A should be life equity, whereby individuals live a life free from bleeding and with levels of mobility that allow them to enjoy a fulfilling and active life.32Currently, achievement of this goal is prevented by limits to the haemostasis that can be achieved with most common treatments.32The results of this study support this, showing that despite being well-treated with FVIII prophylaxis, bleeding is not necessarily well controlled and patients still suffer unacceptable deficits to their joint health, pain, and QoL. This evidence concerns the gene F8 and hemophilia A.