Subsequently (Arjona et al., 2014), identified heterozygous or homozygous CNNM2 mutations in patients with NDDs, revealing a connection between CNNM2 gene mutations and hypomagnesemia, seizures, and impaired intellectual development 1 (HOMGSMR1, OMIM #616418). Here, CNNM2 is linked to Hypomagnesemia.