In addition, CNNM2 has also been implicated in the development of hypertension (Funato et al., 2017), intracranial aneurysm (Liu M. et al., 2023; Wu et al., 2024), myocardial infarction (Matsuoka et al., 2015), pulmonary hypertension (Wang et al., 2021), and sleep apnea (Gui et al., 2024). This evidence concerns the gene CNNM2 and Dilatation of the cerebral artery.