SATB1 and autism: This hypothesis is based on the fact that (1) known causative genes for autism subtypes are components of the multi-subunit complexes that carry this process, which was likely overlooked previously due to the confusing nomenclature of the system, (2) the SATB1 protein that targets one of our significantly enriched transcription factor binding sites is a component of this same system, and (3) the remaining two proteins are likely regulators of the RNA intermediate necessary to carry out this process.