TP53 and hepatocellular carcinoma: PSAT1 also interacts with the codon 72 polymorphism of p53 (p5372p) competing with PPARγ coactivator-1α for binding to p5372p and thereby dissociating the former and activating oxidative phosphorylation and the TCA, whereas PSAT1 knockdown significantly reduced migration in hepatocellular carcinoma cells 55.