CD4 and tuberculosis: The diagnostic yield of Urine-XPU was equal to or higher than that of Sputum-XPU in the subgroups with lactate ≥ 2.5 mmol/L, haemoglobin ≤ 8 g/dL, and CD4 ≤ 200 cells/μL and in those with TB-BSI (Figure 3b, c, d and e).