Moreover, we discovered α-syn protein interactors that have been previously linked to PD through whole exome sequencing, gene expression analysis or transcriptomic analysis (BLTP3A,68,69 NCAPH,70 MIB1,71 PSMD8,70,72 RRM2,73 SART3,70,74 UBFD1,75 CENPF,76,77 LTV1,78 JPT1,79 and HOOK170) or linked to changes in protein levels in PD patients or models (WDR44,80 ANKRD27,81,82 PSMD8,83,84 RRM2,85 and RBBP786,87). Here, PSMD8 is linked to Parkinson disease.