CMTM6 and oral cavity squamous cell carcinoma: Consistently, Mohapatra and colleagues demonstrated that membrane-bound ENO1 interacted with CKLF Like MARVEL Transmembrane Domain Containing 6 (CMTM6) and subsequently stabilized CMTM6 protein, which contributed to cisplatin resistance via activation of Wnt signaling in oral squamous cell carcinoma (Mohapatra et al., 2021).