These pathological phenotypes closely resemble the immunopathological processes mediated by Tnfsf15. Therefore, on the basis of the consistency between pathological phenotypes, transcriptomic analysis, and validation results, it is speculated that Tnfsf15 is a key host molecule regulated by the S. agalactiae BP, AP1, and SrtC gene clusters during host infection. Here, TNFSF15 is linked to infection.