Compared to the model rats, L. reuteri significantly reduced various LF-related indicators, including serum levels of AST, ALT, and ALP(Fig.8A-C), pro-inflammatory factors in the liver(Fig.8D-F), collagen fiber deposition in the liver, hepatic steatosis and inflammatory infiltration, and histological damage in the colon tissues (Fig. 8G–I). The gene discussed is GPT; the disease is Hepatic steatosis.