Pre-operative serum CA-125 levels were higher in the bilateral cyst group [median: 24.5 U/mL (IQR: 14.0–54.0)] than in the unilateral group [16.0 U/mL (IQR: 10.0–30.0)], although this difference was not statistically significant (p = 0.147). Here, MUC16 is linked to cyst.