In TIMM23-knockdown human embryonic kidney 293 T (HEK293T) cells, undegraded PINK1 accumulated (Fig. 5B), whereas TIMM23 expression remained unchanged in lung squamous cell carcinoma cell lines H226 and H520 despite variations in BRF2 and SLC8A3 levels (Fig. 5C). The gene discussed is PINK1; the disease is squamous cell lung carcinoma.