Fold-change values of the densitometric levels of the HECA-452 staining of these blots were statistically analyzed by using a two-tailed t test, and this analysis indicated a significant difference between the densitometry-quantified expression of CD45RABC-E derived from CD34+ AML as compared with native CD34+ HSPCs (mean fold-change AML/HSPCs = 25.8; p < 0.01; Fig. S4B). The gene discussed is CD34; the disease is acute myeloid leukemia.