Although there is limited data on structural and/or functional changes resulting from citrullination, the few existing studies on albumin citrullination in RA synovial fluid (38, 39), non-RA synovial fluid (40), both healthy (41) and diseased tissues (42), and various animal albumins (43, 44, 45) have collectively reported all of the same citrullinated sites in included in the present study. The gene discussed is ALB; the disease is rheumatoid arthritis.