NFKB1 and cardiomyopathy: The complexity of the clinical phenotype in cardiomyopathies suggests the involvement of multiple pathogenic pathways, a notion that is supported by the evidence of dysregulation of the canonical WNT, Hippo, nuclear factor κB1 (NF-κB1), and ubiquitin/proteasome pathways, as well as the metabolic pathways, among others (9–13).