Bleomycin increases multiple fibroproliferative chemokines and cytokines, such as CCL2, CCL5, CXCL10, CCL11, BAFF, IL-12p70, IL-2R, IL-1b, TNFa, IL-6, and LIF, as we have documented in mouse BALF and as has been observed in BALF from patients with IPF (43–50). This evidence concerns the gene CCL5 and idiopathic pulmonary fibrosis.