Analysis of PPAR signaling pathway-related genes in liver samples revealed that, compared to those in the IUGR mice, the levels of Ppara, Rxra, and Fabp3 mRNA in IUGR + ICA mice were significantly higher, and the levels of Tlr4, Pparg, and Cd36 mRNA were significantly lower. The gene discussed is PPARA; the disease is fetal growth restriction.