In this study, through the detection of Ki67 and PCNA index and TUNEL apoptosis fluorescence intensity in tumor tissue, it was shown that the expression of Ki67 and PCNA protein in tumor tissue of mice in the model group was high, while the TUNEL apoptosis fluorescence intensity was very low, indicating that tumor cells in tumor tissue had good proliferation ability and little apoptosis. Here, PCNA is linked to neoplasm.