Notably, in lung adenocarcinoma (LUAD) and LUSC, NUP153 expression was significantly negatively correlated with immune-related genes; whereas, in pancreatic ductal adenocarcinoma (PAAD) and prostate cancer (PRAD), a positive correlation was observed (Figure 7A). The gene discussed is NUP153; the disease is pancreatic ductal adenocarcinoma.