In cholangiocarcinoma (CHOL), colorectal adenocarcinoma (COAD), head and neck squamous cell carcinoma (HNSC), lung squamous cell carcinoma (LUSC), and stomach adenocarcinoma (STAD, a type of gastric cancer), NUP153 expression was higher than in normal human tissues, while in kidney chromophobe (KICH) and thyroid cancer (THCA), expression was significantly downregulated (Figures 1A, B). The gene discussed is NUP153; the disease is thyroid cancer.