Zhang et al., 2019 (56) showed that low IL-24 concentration promotes FoxP3 mRNA expression in tumor-infiltrating T cells, whereas high concentrations decrease Tregs percentage, FoxP3 mRNA expression, and IL-10/IL-35 secretion in cells obtained from patients with colorectal adenocarcinoma. The gene discussed is FOXP3; the disease is colorectal adenocarcinoma.