Furthermore, pathway interaction analyses revealed that CLEC4A was significantly associated with Allograft Rejection, Butanoate Metabolism, Graft-versus-host Disease, Histidine Metabolism, Systemic Lupus Erythematosus, and Valine, Leucine, and Isoleucine Degradation pathways (Figure 6D). The gene discussed is CLEC4A; the disease is systemic lupus erythematosus.