In contrast, median CRP was above the reference range (<10.5 mg/L) in dogs with nSIRS (100.7 mg/L; IQR 67–141.9) or sepsis (131.9 mg/L; IQR 75.7–194.8) and significantly decreased within the first 4 days of successful antimicrobial treatment of sepsis. Here, CRP is linked to Sepsis.