AIP and hypertensive disorder: Among postmenopausal women, the highest AIP quartile (Q4) showed a 58% increased risk of developing pre-hypertension and hypertension relative to baseline (OR:1.58, 95% CI:1.20 to 2.07, P=0.001), whereas the corresponding risk increase in premenopausal women was 38% (OR:1.38, 95% CI:1.07 to 1.72, P=0.008) (Table 8, Figure 8).