We previously generated Nexmif knockout (KO) male and heterozygous (HET) female mouse models which demonstrate ASD-like phenotypes (repetitive behaviors, impaired communication, and altered social preference), accompanied by the presence of anxiety, restrictive behaviors, and deficits in learning and memory at adult ages (Gilbert et al., 2020; O’Connor et al., 2024). The gene discussed is NEXMIF; the disease is Anxiety.