RYR2 and catecholaminergic polymorphic ventricular tachycardia: As RYR2 exon 3 deletion syndrome shows complex CPVT-like phenotypes, including sinus node dysfunction, atrial tachycardia, and atrioventricular node conduction disorder (Steinberg et al., 2023), the patients may present with additional cardiovascular symptoms rather than those of CPVT in the future.