KCNQ1OT1 was the lncRNA with the largest Degree value in the ceRNA network topology; hsa-mir-98-5p was the miRNA with the largest Degree value in the ceRNA network; IL10, CXCL8 and PTGS2 were mRNAs with the same Degree value in the ceRNA network, and there were mutual regulatory effects between these lncRNAs, miRNAs and mRNAs (Figure 9A), suggesting that these ceRNA networks may be key ceRNA network mechanisms in gout. The gene discussed is CXCL8; the disease is gout.