NFKB1 and gout: The results showed that a total of 76 potential transcription factor binding sites were significantly enriched in the promoter region of key genes in the JASPAR database, among which CEBPB, STAT3, RELA and NFKB1 were common transcription factors of the 3 key genes, suggesting that they may play an important role in the regulation of gout key genes (Figure 9B).