MMP8 and obesity due to melanocortin 4 receptor deficiency: Considering that the aforementioned analysis enriched multiple lipid metabolic pathways, it can be inferred that APOD, MMP8, and LTF regulate inflammation and oxidative stress by participating in FAO processes and contribute to chronic inflammatory diseases such as obesity (Fyfe-Desmarais et al., 2023; Yu and Li, 2022).