At the same time, QSYQ reduced the intensity of Vimentin, α-SMA and TGF-β in cardiac spheroids (Figure 8A) and Col1a1, Col3a1 and Postn mRNA expression (1.72 ± 0.10 vs. 2.50 ± 0.38, 1.17 ± 0.10 vs. 1.57 ± 0.28, 1.33 ± 0.10 vs. 1.99 ± 0.14) in CF cells, compared with Ang II group. This evidence concerns the gene COL1A1 and cystic fibrosis.