Although STZ-injected mice displayed a decrease in overall LAMP1 staining (two-way ANOVA: diabetes factor, F(1, 18) = 5.912, P< 0.05) (Fig. 7C), post-hoc tests did not reveal significant inter-group differences, suggesting only subtle lysosomal changes in the hippocampus at this age. The gene discussed is LAMP1; the disease is diabetes mellitus.