SPINK1 and hereditary disease: Hereditary pancreatitis (HP) is a rare genetic disorder characterized by recurrent episodes of acute or chronic pancreatitis, typically manifesting before the age of 20. It is most commonly linked to pathogenic mutations in the genes encoding protease serine 1 (PRSS1), serine peptidase inhibitor Kazal type 1 (SPINK1), and the cystic fibrosis transmembrane conductance regulator (CFTR) [2].