In agreement with previous studies, USP10 acts as an oncoprotein in hepatocellular carcinoma,[20] esophageal squamous cell carcinoma,[21] glioblastoma,[23] and acute myeloid leukemia[26] through the stabilization of YAP, ANLN, RUNX1, and FLT3. The gene discussed is RUNX1; the disease is esophageal squamous cell carcinoma.