The KEGG pathway enrichment analysis (Fig. 5B) showed that the targets of scorpion and centipede-derived compounds in improving asthma were predominantly closely linked to several key pathways: the calcium signaling pathway, estrogen signaling pathway, arachidonic acid (AA) metabolism pathway, inflammatory mediator and transient receptor potential (TRP) signaling pathway, vascular smooth muscle contraction, thyroid hormone signaling pathway, sphingolipid signaling pathway, interleukin (IL)-17 signaling pathway, insulin resistance, and human cytomegalovirus infection. Here, IL17A is linked to asthma.