CASP1 and asthma: In our previous study, we also found that scorpion and centipede-derived drug pairs improved asthma-induced inflammation in mice by increasing the M2 macrophage-derived exosome miR-30b-5p, reducing the expression of nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3), caspase-1, and IL-1β, and reducing mitochondrial swelling [19].