Tim4 protein in peritoneal macrophages can tether apoptotic cells to mediate the efferocytosis of macrophages, hinting that Tim4+ TAMs might eliminate apoptotic cancer cells or release immunosuppressive cytokines to regulate immune responses, there by promoting tumour metastasis and growth and even evading treatment‐induced apoptosis with hazardous outcomes [59, 60]. Here, TIMD4 is linked to cancer.