However, F0-HFD sires present very mild hyperinsulinemia (F0-HFD: 130.1 ± 26.4; F0-CON: 117.3 ± 8.18 pM, r = 0.3, p = 0.14), (Fig. 1F), and still possess physiological cholesterol levels and liver functionality, as shown by triglycerides levels, HDL, LDL, ALT and AST, that are not significantly different from the control F0-CON group (Table 1). This evidence concerns the gene GPT and hyperinsulinism.