Of the top 10 ranked contextual parameters observed for longer survivors, 1 parameter was large tumor area, 3 related to high densities of T cell subsets in different compartments, 3 to shorter distances among CD4 T cells, among TAMs and between NK and CD8 T cells, and 3 to longer distances between tumor cells and either TAMs, CD4 T cells, and other tumor cells (Fig. 5B). This evidence concerns the gene CD8A and neoplasm.