For example, with inForm and QuPath highest densities of immune effector cell populations in border-stroma of both inflamed and non-inflamed tumor tissues were observed (Supplementary Fig. 1A), as well as much lower densities in the center-stroma of the non-inflamed tumors and shorter distances to CD8 T cells in inflamed tumors (Supplementary Fig. 1B). This evidence concerns the gene CD8A and neoplasm.