The 10 parameters that drive the classifier (Fig. 5B) comprise: tumor area; density of CD4 T cells in tumor and stroma, and that of CD8 T cells in stroma; as well as the CD4-CD4; CD8-CD56; CD68-CD68; CD4-CK; CD68-CK; and CK-CK distances. The gene discussed is CD8A; the disease is neoplasm.