IL6 and neoplasm: CAFs interact with other key immunomodulatory cells including tumor‐associated macrophages (TAMs), regulatory T cells (Tregs), and myeloid‐derived suppressor cells (MDSCs) by releasing growth factors and proinflammatory cytokines, such as transforming growth factor β (TGF-β), vascular endothelial growth factor (VEGF), and interleukin-6 (IL-6)50,59–65.