Our observation also aligns with a study by Michelet et al., who demonstrated that blocking lipid transport into mitochondria reversed metabolic paralysis in NK cells, subsequently restoring their cytotoxicity against tumor cells.35 Therefore, reversing the metabolic defects associated with lipid uptake by blocking CPT1, could allow Vγ9Vδ2-T cells to regain their cytotoxic capabilities. This evidence concerns the gene CPT2 and neoplasm.