Differential gene expression analysis of all stromal cells from JIA synovial tissue revealed two gene modules (S5 & S6 modules) upregulated in both SOX5+ fibroblasts and FLI1+ capillary cells (Fig. 8C), another cell type enriched in JIA compared with adult tissue (Fig. 8, A and B, Fig. 7G). The gene discussed is FLI1; the disease is juvenile idiopathic arthritis.