SLC31A1 and cancer: The study showed that there was a significant association of the same cuproptosis-related gene with immune-related scores in various cancers; especially, most cuproptosis-related genes had negative correlations with immune-related scores in different cancers (Fig 6A), while SLC31A1 had positive association with StromalScore, ImmuneScore and EstimateScore in LAML (Fig 6B–6D).In addition, there were significant correlations between the expressions of cuproptosis-related genes and cells in TME (S8A, S8H Fig), which suggested that cuproptosis might have a capacity to regulate the cells in TME.