We then utilized logistic regression analysis to construct an HCC prognosis model using the expression data of the above 9 genes, calculating a Predictive Score for each sample: Predictive Score = CYYR1 * 1.422 + GCHFR * 1.276 + COL15A1 * 0.580 + ECI1 * 0.567 + TM4SF18 * 0.212 - SPP1 * 0.120 - PLOD2 * 0.255 - CLEC14A * 0.717 - ROBO4 * 1.134 (Table 2). Here, SPP1 is linked to hepatocellular carcinoma.