In addition, we also compared the mice treated with CLL and PBS induced by excessive APAP, and found that the liver injury of CLL‐treated mice was aggravated (Figure S4A), serum ALT and AST levels were also significantly increased, and the glutathione level that antagonises APAP‐induced liver injury was significantly decreased after CLL treatment (Figure S4B,C). The gene discussed is GPT; the disease is B-cell chronic lymphocytic leukemia.