NQO1 and neoplasm: By contrast, both combined treatment with cabozantinib + GDC‐0326 and single‐drug treatment with CB‐839 reduced overall NQO1 expression and, notably, altered the distribution of NQO1 similar to the tissue distribution of NQO1‐positive and ‐negative cells in the primary tumor (Figure 5L,M; compare with Figure 5F).