HLA-C and neoplasm: Besides, key genes related to immune factors imply that these genes may be involved in several immunological processes: recruiting or excluding immune cells from the tumor site (e.g., through chemokine signaling); activating or suppressing immune responses, such as by influencing immune checkpoint pathways; altering antigen presentation via MHC molecules, which affects the visibility of tumor cells to the immune system; shaping immune cell phenotypes, for example, by skewing macrophages toward either the pro‐tumor M2 or anti‐tumor M1 subtype [46].