Higher DF intake in non-APOE4 carriers is associated with decrease in Corynebacterium, a bacteria linked to conditions such as depression,55 schizophrenia,56 and autism spectrum disorders.57 DF intake also correlated with Defluviitaleaceae UCG-011 in non-APOE4 carriers, which may help maintain cognitive function through the gut-brain axis.58 Additionally, Bilophila, Eubacterium eligens, Sutterella, Bacteroides, and Parabacteroides were associated with DF intake in non-APOE4 carriers. This evidence concerns the gene APOE and depressive symptom measurement.