Compared to cationic nanoparticles alone, swallowing nanovaccines could augment the antigen load, further strengthen the immune response due to the existence of peptide‐MHC, and could home to lymph nodes and interact with DCs by means of their homotypic targeting characteristics.[89] EVs derived from neutrophils are capable of triggering apoptosis in tumor cells but not in normal cells by transporting cytotoxic proteins such as FasL, granzyme, perforin, and initiating the caspase signaling pathway.[90]. The gene discussed is PRF1; the disease is neoplasm.