PDPN and amyotrophic lateral sclerosis: The increases, particularly in Vegfd mRNA, and Lyve1 and Pdpn protein levels in p120 EDL (Fig. 4A and Fig. 5B, respectively) and of Pdpn mRNA in p120 lumbar SPC (Fig. 4C), in the context of elevated inflammation (Fig. 4), suggested an expansion in lymphatic capillary coverage, i.e. inflammatory lymphangiogenesis, in these two tissues in ALS mice.