The RNA sequencing database TCGA (The Cancer Genome Atlas) and the protein quantitation database CPTAC (Clinical Proteomic Tumor Analysis Consortium) revealed that compared with that in normal tissues, Gal-3 expression in pancreatic cancer tissues was significantly elevated at both the RNA and protein levels (Fig. 1A–D). The gene discussed is LGALS3; the disease is familial pancreatic carcinoma.