Research has demonstrated that DEPDC1 is highly expressed in a majority of tumors, including human osteosarcoma (5, 6), hepatocellular carcinoma (10, 11), nephroblastoma (7), anaplastic thyroid carcinoma (8), colorectal cancer (4), and oral squamous cell carcinoma. This evidence concerns the gene DEPDC1 and thyroid gland undifferentiated (anaplastic) carcinoma.