DEPDC1 and osteosarcoma: DEPDC1 exhibits overexpression in various malignant tumors, including oral squamous cell carcinoma (4), human osteosarcoma (5, 6), nephroblastoma (7), anaplastic thyroid carcinoma (8), non-small cell lung cancer (9), hepatocellular carcinoma (10, 11), and colorectal cancer (12).