Histopathological results confirmed two different tumors(Figure 3): Brachyury (Chordoma+), EMA (Chordoma+), CK8/18 (Chordoma and Pituitary neuroendocrine tumor), CKp (Chordoma and Pituitary neuroendocrine tumor+), PIT-1 (Pituitary neuroendocrine tumor+), GH (+), PRL (Focal +/-), Syn (Pituitary neuroendocrine tumor+), Vimentin (+), GFAP (-), Olig-2 (-), S-100 (-), p53 (Wild type), CK5/6 (Focal +/-), T-PIT (-), SF-1 (-), FSH (-), Ki67 (3%+), ACTH (Focal +/-), TSH (-), LH (-). This evidence concerns the gene PLOD1 and chordoma.